Anti-CDKN1A monoclonal antibody (DMAB5419MH)

Mouse anti-Human CDKN1A monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
EDT-60.3
Species Reactivity
Human
Immunogen
BALB/C mice were injected with a full length human recombinant p21 protein.
Conjugate
Unconjugated

Target


Alternative Names
CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1; Cyclin-dependent kinase inhibitor 1; CDK-interacting protein 1; CAP20
Entrez Gene ID
UniProt ID

Product Background


Pathway
AKT phosphorylates targets in the cytosol; AMPK signaling; Adipogenesis; Alpha6-Beta4 Integrin Signaling Pathway; Bladder cancer; C-MYB transcription factor network; Cell Cycle Checkpoints; Cell Cycle, Mitotic; Cell cycle; Chronic myeloid leukemia; Class

Citations


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References


Liszka, L; et al. DUCTAL ADENOCARCINOMA OF THE PANCREAS USUALLY RETAINED SMAD4 AND p53 PROTEIN STATUS AS WELL AS EXPRESSION OF EPITHELIAL-TO-MESENCHYMAL TRANSITION MARKERS AND CELL CYCLE REGULATORS AT THE STAGE OF LIVER METASTASIS. POLISH JOURNAL OF PATHOLOGY 65:100-112(2014).
Galmarini, CM; Bouchet, BP; et al. A p21/WAF1 mutation favors the appearance of drug resistance to paclitaxel in human noncancerous epithelial mammary cells. INTERNATIONAL JOURNAL OF CANCER 119:60-66(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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