Anti-Human Nucleophosmin (nucleolar phosphoprotein B23 (DMAB5493MH)

Mouse anti-Human Nucleophosmin (nucleolar phosphoprotein B23 [clone OB25] for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG
Clone
OB25
Immunogen
BALB/C mice were immunized with GST fusion protein containing the N-terminal part of nucleophosmin fused to 14 amino acid of ALK protein.
Conjugate
Unconjugated

Target


Alternative Names
NPM1; nucleophosmin (nucleolar phosphoprotein B23, numatrin); B23; NPM; nucleophosmin; numatrin
Entrez Gene ID
UniProt ID

Product Background


Pathway
Aurora B signaling; BARD1 signaling events; Chromosome Maintenance; Deposition of New CENPA-containing Nucleosomes at the Centromere; HIF-1-alpha transcription factor network; HIV Infection; Host Interactions of HIV factors; Interactions of Rev with host

Citations


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References


Zhu, XP; Ma, YH; et al. Novel agents and regimens for acute myeloid leukemia: 2009 ASH annual meeting highlights. JOURNAL OF HEMATOLOGY & ONCOLOGY 3:-(2010).
Falini, B; Martelli, MP; et al. Cytoplasmic mutated nucleophosmin is stable in primary leukemic cells and in a xenotransplant model of NPMc(+) acute myeloid leukemia in SCID mice. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 93:775-779(2008).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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