Anti-MCL1 monoclonal antibody (DMAB5482MH)

Mouse anti-Human MCL1 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
SD14
Species Reactivity
Human
Immunogen
BALB/C mice were immunized with recombinant human Mcl-1 protein corresponding to amino acid 1-327.
Conjugate
Unconjugated

Target


Alternative Names
MCL1; myeloid cell leukemia sequence 1 (BCL2-related); TM; EAT; MCL1L; MCL1S
Entrez Gene ID
UniProt ID

Product Background


Pathway
Apoptosis; Direct p53 effectors; E2F transcription factor network; HIF-1-alpha transcription factor network; IL-7 Signaling Pathway; IL6-mediated signaling events

Citations


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References


Zhuang, JG; Hawkins, SF; et al. Akt is activated in chronic lymphocytic leukemia cells and delivers a pro-survival signal: the therapeutic potential of Akt inhibition. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 95:110-118(2010).
Wang, C; Leger, RJS; et al. A collagenous protective coat enables Metarhizium anisopliae to evade insect immune responses. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 103:6647-6652(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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