Anti-MCL1 monoclonal antibody (DMAB5482MH)

Mouse anti-Human MCL1 monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
SD14
Species Reactivity
Human
Immunogen
BALB/C mice were immunized with recombinant human Mcl-1 protein corresponding to amino acid 1-327.
Conjugate
Unconjugated

Target


Alternative Names
MCL1; myeloid cell leukemia sequence 1 (BCL2-related); TM; EAT; MCL1L; MCL1S
Entrez Gene ID
UniProt ID

Product Background


Pathway
Apoptosis; Direct p53 effectors; E2F transcription factor network; HIF-1-alpha transcription factor network; IL-7 Signaling Pathway; IL6-mediated signaling events

Citations


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References


Goval, JJ; Thielen, C; et al. The prevention of spontaneous apoptosis of follicular lymphoma B cells by a follicular dendritic cell line: involvement of caspase-3, caspase-8 and c-FLIP. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 93:1169-1177(2008).
Vikstrom, I; Carotta, S; et al. Mcl-1 Is Essential for Germinal Center Formation and B Cell Memory. SCIENCE 330:1095-1099(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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