Anti-Human Hypoxia-Inducible Factor-1 alpha Antibody (DMAB5439MH)

Mouse anti-Human Hypoxia-Inducible Factor-1 alpha Monoclonal antibody [clone PA13] for IHC, GSA, WB, IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
PA13
Immunogen
BALB/C mice were injected with hHIF-1­ (aa 530-826) protein.
Conjugate
Unconjugated

Target


Alternative Names
HIF1A; hypoxia inducible factor 1, alpha subunit (basic helix-loop- helix transcription factor); HIF1; MOP1; PASD8; bHLHe78
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adipogenesis; HIF-1-alpha transcription factor network; Hypoxic and oxygen homeostasis regulation of HIF-1-alpha; Notch- mediated HES/HEY network; PDGFR-beta signaling pathway; Pathways in cancer; Renal cell carcinoma; Signaling events mediated by VEGFR1

Citations


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References


Mastrogiannaki, M; Matak, P; et al. Hepatic hypoxia-inducible factor-2 down-regulates hepcidin expression in mice through an erythropoietin-mediated increase in erythropoiesis. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL 97:827-834(2012).
Wei, H; Bedja, D; et al. Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-beta signaling. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:E841-E850(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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