Anti-GAD2 monoclonal antibody (CABT-37787MH)

Mouse anti-Human GAD2 monoclonal antibody for WB, IP, FC, RIA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
255
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide: GSGFWSFGSEDGSGDSEN conjugated to KLH, corresponding to amino acids 4-22 of Human GAD65
Conjugate
Unconjugated

Applications


Application Notes
WB: 1μg/ml; Flow Cyt:
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
GAD2; glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); glutamate decarboxylase 2 (pancreatic islets and brain, 65kD); glutamate decarboxylase 2; GAD65; 65 kDa glutamic acid decarboxylase
Entrez Gene ID
UniProt ID

Product Background


Pathway
Alanine and aspartate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Biogenic Amine Synthesis, organism-specific biosystem; Butanoate metabolism, organism-specific biosystem; Butanoate metabolism, conserved biosystem; GABA (gamma-Aminobutyrate) shunt, organism-specific biosystem; GABA (gamma-Aminobutyrate) shunt, conserved biosystem; GABA synthesis, organism-speci

Citations


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References


Howson, JMM; Rosinger, S; et al. Genetic Analysis of Adult-Onset Autoimmune Diabetes. DIABETES 60:2645-2653(2011).
Wan, XX; Guloglu, FB; et al. Recovery From Overt Type 1 Diabetes Ensues When Immune Tolerance and beta-Cell Formation Are Coupled With Regeneration of Endothelial Cells in the Pancreatic Islets. DIABETES 62:2879-2889(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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