Anti-CD3E monoclonal antibody (CABT-31748MH)

Mouse anti-Human CD3E monoclonal antibody for CellAct, FC, IHC-Fr Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
NN0278-4G54
Species Reactivity
Human
Immunogen
Human recombinant CD3 epsilon
Conjugate
Unconjugated

Applications


Application Notes
IHC-Fr: 1/50 - 1/100; Flow Cyt: 1/50 - 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CD3E; CD3e molecule, epsilon (CD3-TCR complex); CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell surface glycoprotein CD3 epsilon chain; CD3E; CD3E antigen epsilon polypeptide
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Downstream TCR signaling, organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem; Generation of second messenger molecules, organism-specifi

Citations


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References


Jury, EC; Kabouridis, PS; et al. Increased ubiquitination and reduced expression of LCK in T lymphocytes from patients with systemic lupus erythematosus. ARTHRITIS AND RHEUMATISM 48:1343-1354(2003).
Nakagawa, R; Vukovic, M; et al. Modulation of PKC-alpha promotes lineage reprogramming of committed B lymphocytes. EUROPEAN JOURNAL OF IMMUNOLOGY 42:1005-1015(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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