Anti-HSPA5 polyclonal antibody (DPABH-26051)

Rabbit anti-Human HSPA5 (full length) polyclonal antibody for ICC/IF, WB, ELISA, IHC-P Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Dog, Human
Immunogen
Recombinant full length Human GRP78 BiP (His tagged at the N terminus).
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 5μg/ml; WB: 1/1000 - 1/2000; IHC-P: 1μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); BIP; MIF2; GRP78; HEL-S-89n
Entrez Gene ID
UniProt ID

Product Background


Pathway
ATF6-alpha activates chaperone genes; Adaptive Immune System; Antigen processing and presentation; Class I MHC mediated antigen processing & presentation

Citations


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References


Fae, KC; da Silva, DD; et al. PDIA3, HSPA5 and vimentin, proteins identified by 2-DE in the valvular tissue, are the target antigens of peripheral and heart infiltrating T cells from chronic rheumatic heart disease patients. JOURNAL OF AUTOIMMUNITY 31:136-141(2008).
Stockton, JD; Merkert, MC; et al. A complex of chaperones and disulfide isomerases occludes the cytosolic face of the translocation protein Sec61p and affects translocation of the prion protein. BIOCHEMISTRY 42:12821-12834(2003).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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