Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5-GTTAATNATTAAC-3.
Pathway
Adipogenesis; FOXA2 and FOXA3 transcription factor networks; Maturity onset diabetes of the young; Presenilin action in Notch and Wnt signaling
Citations
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