Specifications
Immunogen
Recombinant fragment within Human HNF1 aa 35-268. The exact sequence is proprietary.Database link: P20823
Applications
Application Notes
WB: 1/500 - 1/3000;
Target
Alternative Names
HNF1A; HNF1 homeobox A; MODY3, TCF1, transcription factor 1, hepatic; LF B1, hepatic nuclear factor (HNF1), albumin proximal factor; hepatocyte nuclear factor 1-alpha; HNF1; LFB1; HNF-1-alpha; albumin proximal factor; hepatic nuclear factor 1; transcript
Product Background
Antigen Description
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for the expression of several liver specific genes. Binds to the inverted palindrome 5-GTTAATNATTAAC-3.
Pathway
Adipogenesis, organism-specific biosystem; Developmental Biology, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem; Maturity onset diabetes of the young, organism-specific biosystem; Maturity onset diabetes of the young, conserved biosystem; Presenilin action in Notch and Wnt signaling, organism-specific biosystem;
Citations
Publication ()
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COA
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