HMGA1; high mobility group AT-hook 1; HMG-R; HMGIY; HMGA1A; high mobility group protein HMG-I/HMG-Y; HMG-I(Y); high mobility group protein R; high mobility group protein A1; nonhistone chromosomal high-mobility group protein HMG-I/HMG-Y; high-mobility gro
HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
Pathway
2-LTR circle formation; Adipogenesis; Cellular Senescence; DNA Damage/Telomere Stress Induced Senescence
Citations
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