Anti-HCRTR2 polyclonal antibody (DPABH-28210)

Rabbit anti-Mouse HCRTR2 (C-terminal) polyclonal antibody for WB, IHC-P, IHC-Fr, ICC/IF Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide from C-terminal region of Mouse Orexin Receptor 2 conjugated to an immunogenic carrier protein.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/300 - 1/2000; IHC-P: 1/300 - 1/2000; IHC-Fr: 1/300 - 1/2000; ICC/IF: 1/200.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
HCRTR2; hypocretin (orexin) receptor 2; OX2R; mOXR2; mOX2aR; mOX2bR
Entrez Gene ID
UniProt ID

Product Background


Pathway
Class A/1 (Rhodopsin-like receptors); GPCR downstream signaling; Gastrin-CREB signalling pathway via PKC and MAPK; Neuroactive ligand-receptor interaction

Citations


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References


Chen, XY; Li, R; et al. Identification of differentially expressed genes in hypothalamus of chicken during cold stress. MOLECULAR BIOLOGY REPORTS 41:2243-2248(2014).
Tanaka, S; Honda, Y; et al. Detection of autoantibodies against hypocretin, hcrtr1, and hcrtr2 in narcolepsy: Anti-hcrt system antibody in narcolepsy. SLEEP 29:633-638(2006).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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