GMPPB (NP_037466, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. The sequence is MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVL EKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSD
This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Pathway
Amino sugar and nucleotide sugar metabolism; Asparagine N-linked glycosylation; Fructose and mannose metabolism; Metabolism of proteins
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