Anti-GMPPB monoclonal antibody (DMABT-H13850)

Mouse anti-Human GMPPB monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

Online Inquiry Add to basket


Host Species
Antibody Isotype
Species Reactivity
GMPPB (NP_037466,2a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.


Alternative Names
GMPPB; GDP-mannose pyrophosphorylase B; mannose-1-phosphate guanyltransferase beta; KIAA1851; mannose-1-phosphate guanylyltransferase; GTP-mannose-1-phosphate guanylyltransferase beta
Entrez Gene ID
UniProt ID

Product Background

Gene summary
GMPPB (GDP-Mannose Pyrophosphorylase B) is a Protein Coding gene. Diseases associated with GMPPB include muscular dystrophy-dystroglycanopathy, type c, 14 and muscular dystrophy-dystroglycanopathy, type a, 14. Among its related pathways are Metabolism and Transport to the Golgi and subsequent modification. GO annotations related to this gene include GTP binding and mannose-1-phosphate guanylyltransferase activity. An important paralog of this gene is GMPPA. This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Antigen Description
Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A14 (MDDGA14) [MIM:615350]: An autosomal recessive disorder characterized by congenital muscular dystrophy associated with brain anomalies, eye malformations, and profound mental retardation. The disorder includes a severe form designated as Walker-Warburg syndrome and a less severe phenotype known as muscle-eye-brain disease. MDDGA14 features include increased muscle tone, microcephaly, cleft palate, feeding difficulties, severe muscle weakness, sensorineural hearing loss, cerebellar hypoplasia, ataxia, and retinal dysfunction. Note=The disease is caused by mutations affecting the gene represented in this entry. Muscular dystrophy-dystroglycanopathy congenital with mental retardation B14 (MDDGB14) [MIM:615351]: A congenital muscular dystrophy characterized by severe muscle weakness apparent in infancy and mental retardation. Some patients may have additional features, such as microcephaly, cardiac dysfunction, seizures, or cerebellar hypoplasia. Muscular dystrophy-dystroglycanopathy limb-girdle C14 (MDDGC14) [MIM:615352]: An autosomal recessive form of muscular dystrophy characterized by mild proximal muscle weakness with onset in early childhood. Some patients may have additional features, such as mild intellectual disability or seizures. Mannose-1-phosphate guanyltransferase beta is an enzyme that in humans is encoded by the GMPPB gene. 0The function about GMPPB antigen include GTP binding; mannose-1-phosphate guanylyltransferase activity; nucleotide binding; nucleotidyltransferase activity; transferase activity.
Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Asparagine N-linked glycosylation, organism-specific biosystem; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, organism-specific biosystem; Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Metabolic pathways, organism-spe.


Have you cited DMABT-H13850 in a publication? Let us know and earn a reward for your research.


Weuster-Botz, D; Altenbach-Rehm, J; et al. Parallel substrate feeding and pH-control in shaking-flasks. BIOCHEMICAL ENGINEERING JOURNAL 7:163-170(2001).
Lochlainn, LN; Caffrey, P; et al. Phosphomannose isomerase and phosphomannomutase gene disruptions in Streptomyces nodosus: Impact on amphotericin biosynthesis and implications for glycosylation engineering. METABOLIC ENGINEERING 11:40-47(2009).

Custom Antibody Labeling

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews

Write a review, share your experiences with others and get rewarded !

Online Inquiry

Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-GMPPB monoclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket