GMEB1 (NP_077808, 467 a.a. ~ 563 a.a) partial recombinant protein with GST tag. The sequence is TAMQDGSTLGNMTTMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTE GKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED
Conjugate
Unconjugated
Target
Alternative Names
GMEB1; glucocorticoid modulatory element binding protein 1; PIF96; P96PIF; glucocorticoid modulatory element-binding protein 1; GMEB-1; PIF p96; DNA-binding protein p96PIF; parvovirus initiation factor p96;
This gene encodes a member of KDWK gene family which associates with GMEB2 protein. The GMEB1-GMEB2 complex is essential for parvovirus DNA replication. Studies in rat for a similar gene suggest that this genes role is to modulate the transactivation of the glucocorticoid receptor when it is bound to glucocorticoid response elements. Two alternative spliced transcript variants encoding different isoforms exist.
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