Anti-FOXO3 monoclonal antibody (CAB-5582MH)

Mouse Anti-Human FOXO3 monoclonal antibody for ELISA, IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2C22
Species Reactivity
Human
Immunogen
FOXO3A (AAH21224, 361 a.a. ~ 460 a.a) partial recombinant protein with GST tag.MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
FOXO3; forkhead box O3; FKHRL1, FOXO3A; forkhead box protein O3; AF6q21; FOXO2
Entrez Gene ID
UniProt ID

Product Background


Pathway
AKT phosphorylates targets in the nucleus, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class I PI3K signaling events, organism-specific biosystem; Class I PI3K signaling events mediated by Akt, organism-specific biosystem; Developmental Biology, organism-specific biosystem;

Citations


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References


Matsuzaki, H; Ichino, A; et al. Regulation of intracellular localization and transcriptional activity of FOXO4 by protein kinase B through phosphorylation at the motif sites conserved among the FOXO family. JOURNAL OF BIOCHEMISTRY 138:485-491(2005).
Kopycinska, J; Kempinska-Podhorodecka, A; et al. Activation of FoxO3a/Bim axis in patients with Primary Biliary Cirrhosis. LIVER INTERNATIONAL 33:231-238(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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