Anti-FCGRT monoclonal antibody (DCABH-11548) Made to order

Rabbit anti-Human FCGRT monoclonal antibody for WB, ELISA

View other FCGRT antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human FCGRT is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
FCGRT; Fc fragment of IgG, receptor, transporter, alpha; IgG receptor FcRn large subunit p51; alpha chain; FCRN; FcRn alpha chain
Entrez Gene ID
UniProt ID

Product Background


Gene summary
FCGRT (Fc Fragment Of IgG Receptor And Transporter) is a Protein Coding gene. Diseases associated with FCGRT include hypoproteinemia, hypercatabolic and immunoglobulin g deficiency. GO annotations related to this gene include antigen binding and beta-2-microglobulin binding. This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants.
Antigen Description
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene. 0The function about FCGRT antigen include IgG binding; beta-2-microglobulin binding; receptor activity.

Citations


Have you cited DCABH-11548 in a publication? Let us know and earn a reward for your research.

Related Products


Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


Kuo, TT; Aveson, VG; et al. Neonatal Fc receptor and IgG-based therapeutics. MABS 3:422-430(2011).
Passot, C; Azzopardi, N; et al. Influence of FCGRT gene polymorphisms on pharmacokinetics of therapeutic antibodies. MABS 5:614-619(2013).

Online Inquiry

Name:
Phone: *
E-mail Address: *
Service & Products Interested: *
Project Description:
Verification Code: * Please input "diagnostics" as verification code.

Online Inquiry

  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket