Anti-ELK1 (aa 67-166) polyclonal antibody

Species Reactivity

Human

Immunogen

ELK1 (NP_005220, 67 a.a. ~ 166 a.a) partial recombinant protein with GST tag. The sequence is YYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEVSVTSTMPNVAPAAIHAAPGDT VSGKPGTPKGAGMAGPGGLARSSRNEYMRSGLYSTFTIQS

Conjugate

Alternative Names

ELK1; ELK1, member of ETS oncogene family; ETS domain-containing protein Elk-1; ETS-like gene 1; tyrosine kinase (ELK1) oncogene;

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14.

Pathway

Activated TLR4 signalling; B Cell Receptor Signaling Pathway; BDNF signaling pathway; Downstream signaling in naive CD8+ T cells