Anti-ELK1 monoclonal antibody, clone 8F20F9

Clone

8F20F9

Species Reactivity

Human

Immunogen

Recombinant protein corresponding to human ELK1.

Conjugate

Application Notes

WB (1:500-1:2000); ELISA (1:10000) & The optimal working dilution should be determined by the end user.

Alternative Names

ELK1; ELK1, member of ETS oncogene family; ETS domain-containing protein Elk-1; ETS-like gene 1; tyrosine kinase (ELK1) oncogene;

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Pathway

Activated TLR4 signalling, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; BCR signaling pathway, organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; ERK/MAPK targets, organism-specific biosystem;