Anti-eIF3H monoclonal antibody (DCABH-9289)

Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Species Reactivity
Human
Immunogen
Recombinant fragment with tag: YDPIKTAQGS LSLKAYRLTP KLMEVCKEKD FSPEALKKAN ITFEYMFEEV PIVIKNSHLI NVLMWELEKK SAVADKHELL SLASSNHLGK NLQLLMDRV, corresponding to amino acids 152-251 of Human EIF3S3
Conjugate
Unconjugated

Target


Alternative Names
EIF3H; eukaryotic translation initiation factor 3, subunit H; EIF3S3, eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa; eukaryotic translation initiation factor 3 subunit H; eIF3 gamma; eIF3 p40
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Formation of a pool of free 40S subunits, organism-specific biosystem; Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem; GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem; Gene Expression, organism-specific biosystem;

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References


Zhou, F; Roy, B; et al. Translation reinitiation and development are compromised in similar ways by mutations in translation initiation factor eIF3h and the ribosomal protein RPL24. BMC PLANT BIOLOGY 10:-(2010).
Edgett, BA; Fortner, ML; et al. Mammalian target of rapamycin pathway is up-regulated by both acute endurance exercise and chronic muscle contraction in rat skeletal muscle. APPLIED PHYSIOLOGY NUTRITION AND METABOLISM-PHYSIOLOGIE APPLIQUEE NUTRITION ET METABOLISME 38:862-869(2013).

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