The elF3H (eIF3-p40) is a subunit of eukaryotic translation initiation factor4(eIF3) complex that plays a central role in the protein translation initiation. The eIF3 consists of at least 10 subunits ranging from 35 to280kd. elF3-p40 is constitutively expressed in many tissues, including spleen thymus, prostate, colon, ovary, etc. Eukaryotic translation initiation factor 3 subunit H is a protein that in humans is encoded by the EIF3H gene. 0The function about eIF3H antigen include protein binding; contributes_to translation initiation factor activity; contributes_to translation initiation factor activity.
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Formation of a pool of free 4S subunits, organism-specific biosystem; Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem; GTP hydrolysis and joining of the 6S ribosomal subunit, organism-s.