Anti-eIF3H monoclonal antibody (DMABT-H18627)
Mouse anti-eIF3H monoclonal antibody for WB
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Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 to 2.0 μg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
EIF3H; eukaryotic translation initiation factor 3, subunit H; EIF3S3, eukaryotic translation initiation factor 3, subunit4gamma, 40kDa; eukaryotic translation initiation factor4subunit H; eIF3 gamma; eIF3 p40
The elF3H (eIF3-p40) is a subunit of eukaryotic translation initiation factor4(eIF3) complex that plays a central role in the protein translation initiation. The eIF3 consists of at least 10 subunits ranging from 35 to280kd. elF3-p40 is constitutively expressed in many tissues, including spleen thymus, prostate, colon, ovary, etc. Eukaryotic translation initiation factor 3 subunit H is a protein that in humans is encoded by the EIF3H gene. 0The function about eIF3H antigen include protein binding; contributes_to translation initiation factor activity; contributes_to translation initiation factor activity.
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Formation of a pool of free 4S subunits, organism-specific biosystem; Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem; GTP hydrolysis and joining of the 6S ribosomal subunit, organism-s.
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Edgett, BA; Fortner, ML; et al. Mammalian target of rapamycin pathway is up-regulated by both acute endurance exercise and chronic muscle contraction in rat skeletal muscle. APPLIED PHYSIOLOGY NUTRITION AND METABOLISM-PHYSIOLOGIE APPLIQUEE NUTRITION ET METABOLISME 38:862-869(2013).
LUIS, AM; IZQUIERDO, JM; et al. TRANSLATIONAL REGULATION OF MITOCHONDRIAL DIFFERENTIATION IN NEONATAL RAT-LIVER - SPECIFIC INCREASE IN THE TRANSLATIONAL EFFICIENCY OF THE NUCLEAR-ENCODED MITOCHONDRIAL BETA-F1-ATPASE MESSENGER-RNA. JOURNAL OF BIOLOGICAL CHEMISTRY 268:1868-1875(1993).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.