Specifications
Applications
Application Notes
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1.0 to 2.0 μg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
Target
Alternative Names
EIF3H; eukaryotic translation initiation factor 3, subunit H; EIF3S3, eukaryotic translation initiation factor 3, subunit4gamma, 40kDa; eukaryotic translation initiation factor4subunit H; eIF3 gamma; eIF3 p40; eIF3h; eIF-3-gamma; eIF3 p40 subunit; eukary
Product Background
Antigen Description
The elF3H (eIF3-p40) is a subunit of eukaryotic translation initiation factor4(eIF3) complex that plays a central role in the protein translation initiation. The eIF3 consists of at least 10 subunits ranging from 35 to280kd. elF3-p40 is constitutively expressed in many tissues, including spleen thymus, prostate, colon, ovary, etc.
Pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Formation of a pool of free 4S subunits, organism-specific biosystem; Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem; GTP hydrolysis and joining of the 6S ribosomal subunit, organism-s.
Citations
Publication ()
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COA
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