Choline acetyltransferase (abbreviated "ChAT") is an enzyme that is synthesized within the body of a neuron. It is then transferred to the nerve terminal via axoplasmic flow. The role of choline acetyltransferase is to join Acetyl-CoA to choline, resulting in the formation of the neurotransmitter acetylcholine. In humans, the choline acetyltransferase enyzme is encoded by the CHAT gene.
Pathway
Acetylcholine Neurotransmitter Release Cycle; Biogenic Amine Synthesis; Glycerophospholipid metabolism; Neuronal System; Neurotransmitter Release Cycle; Transmission across Chemical Synapses
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