Essential acyltransferase that catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. Required for synthesis and storage of intracellular triglycerides. Probably plays a central role in cytosolic lipid accumulation.
Pathway
Acyl chain remodeling of DAG and TAG; Fat digestion and absorption; Fatty acid, triacylglycerol, and ketone body metabolism; Glycerolipid metabolism; Glycerophospholipid biosynthesis; Metabolism; Metabolism of lipids and lipoproteins; Phospholipid metabol
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COA
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