Anti-Cocaine and Benzoylecgonine monoclonal antibody (DMAB9691)
Mouse anti-Cocaine and Benzoylecgonine monoclonal antibody for ELISA, LFIA
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Cocaine (benzoylmethylecgonine); INN; Cocaine and Benzoylecgonine; C Carrie; " c"
Cocaine (benzoylmethylecgonine) (INN) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is a stimulant of the central nervous system, an appetite suppressant, and a topical anesthetic. Specifically, it is a serotonin–norepinephrine–dopamine reuptake inhibitor, which mediates functionality of these neurotransmitters as an exogenous catecholamine transporter ligand. It is addicting because of the way it affects the mesolimbic reward pathway.
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Gao, DQ; Cho, H; et al. Computational design of a human butyrylcholinesterase mutant for accelerating cocaine hydrolysis based on the transition-state simulation. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 45:653-657(2006).
Sun, W; Luo, C; et al. Effect of polyethylene glycol conjugation on the circulatory stability of plasma-derived human butyrylcholinesterase in mice. CHEMICO-BIOLOGICAL INTERACTIONS 203:172-176(2013).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.