Anti-Cocaine and Benzoylecgonine monoclonal antibody (DMAB9691)

Mouse anti-Cocaine and Benzoylecgonine monoclonal antibody for ELISA, LFIA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
K140Y140
Species Reactivity
N/A
Immunogen
COC-BSA
Conjugate
Unconjugated

Target


Alternative Names
Cocaine (benzoylmethylecgonine); INN; Cocaine and Benzoylecgonine; C Carrie; " c"

Product Background


Antigen Description
Cocaine (benzoylmethylecgonine) (INN) is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is a stimulant of the central nervous system, an appetite suppressant, and a topical anesthetic. Specifically, it is a serotonin–norepinephrine–dopamine reuptake inhibitor, which mediates functionality of these neurotransmitters as an exogenous catecholamine transporter ligand. It is addicting because of the way it affects the mesolimbic reward pathway.

Citations


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References


Gonkowski, S; Kaminska, B; et al. Immunohistochemical distribution of cocaine- and amphetamine-regulated transcript peptide - like immunoreactive (CART-LI) nerve fibers and various degree of co-localization with other neuronal factors in the circular muscle layer of human descending colon. HISTOLOGY AND HISTOPATHOLOGY 28:851-858(2013).
Bruchas, MR; Land, BB; et al. Stress-induced p38 mitogen-activated protein kinase activation mediates kappa-opioid-dependent dysphoria. JOURNAL OF NEUROSCIENCE 27:11614-11623(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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