Specifications
Immunogen
Recombinant full length protein corresponding to Human CYP26A1 aa 1-428.Sequence: MKRRKYGFIYKTHLFGRPTVRVMGADNVRRILLGEHRLVSVHWPASVRTI LGSGCLSNLHDSSHKQRKKVIMRAFSREALECYVPVITEEVGSSLEQWLS CGERGLLVYPEVKRLMFRIAMRILLGCEPQLAGDGDSEQQLVEAFEEMTR NLFSLPIDVPFSGLYRGMKA
Target
Alternative Names
CYP26A1; cytochrome P450, family 26, subfamily A, polypeptide 1; cytochrome P450, subfamily XXVIA, polypeptide 1; cytochrome P450 26A1; CP26; CYP26; P450RAI; P450RAI1; hP450RAI; cytochrome P450RAI; retinoic acid 4-hydroxylase; P450, retinoic acid-inactiva
Product Background
Antigen Description
Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
Pathway
Adipogenesis; Biological oxidations; Cytochrome P450 - arranged by substrate type; Metabolism; Nuclear receptors in lipid metabolism and toxicity; Phase 1 - Functionalization of compounds; Retinol metabolism
Citations
Publication ()
Have you cited DPABH-09409 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
