Specifications
Immunogen
A synthetic peptide corresponding to internal region of mouse Cyp1a2. The sequence is C-HSENYKDNGGLIPEEK
Applications
Application Notes
ELISA: 1:32000; WB: 1-3 μg/mL. & The optimal working dilution should be determined by the end user.
Target
Alternative Names
CYP1A2; cytochrome P450, family 1, subfamily a, polypeptide 2; CP12; Cyp1a1; P450-3; cytochrome P450 1A2; CYPIA2; cytochrome P450-P2; cytochrome P450-P3; aromatic compound inducible; cytochrome P450, 1a2, aromatic compound inducible; cytochrome P450 famil
Product Background
Antigen Description
CYP1A2 (cytochrome P450, family 1, subfamily A, polypeptide 2) is a protein-coding gene. Diseases associated with CYP1A2 include porphyria cutanea tarda, and hemoglobin e - beta-thalassemia, and among its related super-pathways are Tamoxifen Pathway, Pharmacokinetics and Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET). GO annotations related to this gene include iron ion binding and enzyme binding. An important paralog of this gene is CYP1B1.
Pathway
Aflatoxin B1 metabolism; Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2; Caffeine metabolism; Chemical carcinogenesis
Citations
Publication ()
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COA
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