Anti-CXCL11 monoclonal antibody [Biotin]

Antibody Isotype

IgG1

Clone

33G2

Species Reactivity

Human

Immunogen

Recombinant full length Human CXCL11 expressed in E coli. (O14625).

Conjugate

Biotin

Application Notes

WB: 1/1000; Sandwich ELISA: 0.125 - 0.25 μg/ml;

Alternative Names

CXCL11; chemokine (C-X-C motif) ligand 11; SCYB9B, SCYB11, small inducible cytokine subfamily B (Cys X Cys), member 11; C-X-C motif chemokine 11; b R1; H174; I TAC; IP 9; beta-R1; small inducible cytokine B11; small-inducible cytokine B11; interferon gam

Entrez Gene ID

6373

UniProt ID

O14625

Antigen Description

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.

Pathway

CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;