Anti-CXCL11 monoclonal antibody

Antibody Isotype

IgG

Clone

FQS22187

Species Reactivity

Mouse, Rat, Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human CXCL11 aa 1 to the C-terminus (Cysteine residue). The exact sequence is proprietary.Database link: O14625

Conjugate

Unconjugated

Application Notes

ICC/IF: 1/50 - 1/100; WB: 1/1000 - 1/5000.

Alternative Names

CXCL11; chemokine (C-X-C motif) ligand 11; SCYB9B, SCYB11, small inducible cytokine subfamily B (Cys X Cys), member 11; C-X-C motif chemokine 11; b R1; H174; I TAC; IP 9; beta-R1; small inducible cytokine B11; small-inducible cytokine B11; interferon gam

Entrez Gene ID

6373

UniProt ID

O14625

Antigen Description

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.

Pathway

CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More