Anti-CRYAB polyclonal antibody (DPABH-00332)
Rabbit anti-Human CRYAB (C-terminal) polyclonal antibody for WB, IHC-P
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Synthetic peptide, conjugated to KLH derived from sequence near the carboxy-terminus of Human Alpha B Crystallin.
WB: 1/1000; IHC-P: 10 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
CRYAB; crystallin, alpha B; MFM2; CRYA2; CTPP2; HSPB5
Protein processing in endoplasmic reticulum;
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Volkmann, J; Reuning, U; et al. High expression of crystallin B represents an independent molecular marker for unfavourable ovarian cancer patient outcome and impairs TRAIL- and cisplatin-induced apoptosis in human ovarian cancer cells. INTERNATIONAL JOURNAL OF CANCER 132:2820-2832(2013).
van Noort, JM; Bsibsi, M; et al. alpha B-Crystallin Is a Target for Adaptive Immune Responses and a Trigger of Innate Responses in Preactive Multiple Sclerosis Lesions. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 69:694-703(2010).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.