Anti-CRYAB monoclonal antibody (DCABH-619)

Mouse anti-Human CRYAB monoclonal antibody for WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4F4
Species Reactivity
Human
Immunogen
Protein expressed in 293T cells transfected with Human Alpha B Crystallin expression vector.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CRYAB; crystallin, alpha B; CRYA2; alpha-crystallin B chain; HSPB5; heat shock protein beta-5
Entrez Gene ID
UniProt ID

Product Background


Pathway
Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem;

Citations


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References


Volkmann, J; Reuning, U; et al. High expression of crystallin B represents an independent molecular marker for unfavourable ovarian cancer patient outcome and impairs TRAIL- and cisplatin-induced apoptosis in human ovarian cancer cells. INTERNATIONAL JOURNAL OF CANCER 132:2820-2832(2013).
Ousman, SS; Tomooka, BH; et al. Protective and therapeutic role for alpha B-crystallin in autoimmune demyelination. NATURE 448:474-U7(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Order Info: Anti-CRYAB monoclonal antibody

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