Anti-CREB1 monoclonal antibody (DCABH-6460) Knockout Validated

Mouse anti-Human CREB1 monoclonal antibody for ICC/IF, WB, IP, IHC-P, ELISA

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
MC0
Species Reactivity
Mouse, Rat, Human, African green monkey
Immunogen
Recombinant full length protein corresponding to Human CREB aa 1-341.Sequence: MTMESGAENQ QSGDAAVTEA ENQQMTVQAQ PQIATLAQVS MPAAHATSSA PTVTLVQLPN GQTVQVHGVI QAAQPSVIQS PQVQTVQSSC KDLKRLFSGT QISTIAESED SQESVDSVTD SQKRREILSR RPSYRKILND LSSDAPGVPR IEEEKSEEET
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 1/500; WB: 1/500; IHC-P: 1/200; ELISA: 0.1 - 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CREB1; cAMP responsive element binding protein 1; cyclic AMP-responsive element-binding protein 1; CREB-1; transactivator protein; active transcription factor CREB
Entrez Gene ID
UniProt ID

Product Background


Pathway
AKT phosphorylates targets in the nucleus, organism-specific biosystem; ATF-2 transcription factor network, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Beltran, WA; Allore, HG; et al. CREB1/ATF1 Activation in Photoreceptor Degeneration and Protection. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 50:5355-5363(2009).
Mezawa, M; Araki, S; et al. Regulation of human bone sialoprotein gene transcription by platelet-derived growth factor-BB. GENE 435:80-87(2009).

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