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References
Perioperative Medicine for Older People
ANNALS ACADEMY OF MEDICINE SINGAPORE
Authors: Rogerson, Andrew; Partridge, Judith S. L.; Dhesi, Jugdeep K.
Global demographic changes have resulted in an older, frailer surgical population with significant multimorbidity causing higher frequency of adverse postoperative outcomes. The need for restructuring of perioperative care pathways to address this issue has been recognised. Comprehensive geriatric assessment (CGA) and optimisation are emerging as innovative perioperative pathways.This paper describes one centre's approach in applying CGA in the surgical setting and presents the evidence in support of this. Similar models are being established in Singapore in hip fracture, colorectal and vascular populations. The challenges in the widespread adoption of such models of care are similar across settings. The global nature of translation is also discussed in this paper.
Microfluidic spinning of poly (methyl methacrylate)/konjac glucomannan active food packaging films based on hydrophilic/hydrophobic strategy
Here, inspired by the hydrophilic/hydrophobic theory, a novel konjac glucomannan/poly (methyl methacrylate)/chlorogenic acid (KGM/PMMA/CGA) food packaging film was successfully fabricated via microfluidic spinning technology (MST). The results of fourier transform infrared spectroscopy and x-ray diffraction confirmed the formation of hydrogen bonds in the films, which lead to the enhanced mechanical properties. Thermogravimetric analysis and differential scanning calorimetry showed excellent thermal stability of the films. Water vapor permeability (1.47x10(-5) +/- 0.11 g/(m.h.kPa)) and water contact angle (89.2 degrees) measurement proved that the films were hydrophobic. The good swelling degree (85.18 +/- 15.65%) indicated film's potentials in releasing CGA. More importantly, KGM played a key role in the antibacterial activities against Staphylococcus aureus (8.5 +/- 3.5 mm) and Escherichia coli (6.5 +/- 2.1 mm) by utilizing its hydrophilicity. Thus, our present work may provide a new idea for constructing active food packaging films with significant performances based on hydrophilic/hydrophobic strategy.