Specifications
Immunogen
Recombinant Human Cdc6 protein.
Applications
Application Notes
WB: 1 - 2 μg/ml; IP: 2 μg/mg of lysate;
Target
Alternative Names
CDC6; cell division cycle 6 homolog (S. cerevisiae); CDC6 (cell division cycle 6, S. cerevisiae) homolog , CDC6 cell division cycle 6 homolog (S. cerevisiae) , CDC18L; cell division control protein 6 homolog; p62(cdc6); CDC6-related protein; cdc18-relate
Product Background
Antigen Description
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Pathway
Activation of ATR in response to replication stress, organism-specific biosystem; Activation of the pre-replicative complex, organism-specific biosystem; Assembly of the pre-replicative complex, organism-specific biosystem; Association of licensing factors with the pre-replicative complex, organism-specific biosystem; CDC6 association with the ORC:origin complex, organism-specific biosystem; CDK-mediated phosphorylation and removal of Cdc6, organism-specific biosystem; CDT1 association with the CDC6:ORC:origin complex, organism-specific biosystem.
Citations
Publication ()
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COA
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