Specifications
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)
Applications
Application Notes
WB: 1/1000 - 1/10000; IHC-P: 1/100 - 1/250; ICC/IF: 1/100 - 1/250.
Target
Alternative Names
CBS; cystathionine-beta-synthase; cystathionine beta-synthase; HIP4; beta-thionase; serine sulfhydrase; methylcysteine synthase;
Product Background
Antigen Description
Only known pyridoxal phosphate-dependent enzyme that contains heme. Important regulator of hydrogen sulfide, especially in the brain, utilizing cysteine instead of serine to catalyze the formation of hydrogen sulfide. Hydrogen sulfide is a gastratransmitter with signaling and cytoprotective effects such as acting as a neuromodulator in the brain to protect neurons against hypoxic injury.
Pathway
Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Cysteine biosynthesis, homocysteine + serine => cysteine, organism-specific biosystem; Cysteine biosynthesis, homocysteine + serine => cysteine, conserved biosystem; Cysteine formation from homocysteine, organism-specific biosystem;
Citations
Publication ()
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COA
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