Specifications
Immunogen
Synthetic peptide: C-DYPDSYQDTYKPH, corresponding to near C terminal amino acids 491-503 of Human CACNB4
Applications
Application Notes
Peptide ELISA: antibody detection limit dilution 1:4,000. WB: Use at a concentration of 0.2 - 0.6 μg/ml. Detects a band of approximately 58 kDa (predicted molecular weight: 58 kDa).
Target
Alternative Names
CACNB4; calcium channel, voltage-dependent, beta 4 subunit; EA5; EJM; CAB4; EIG9; EJM4; EJM6; CACNLB4; voltage-dependent L-type calcium channel subunit beta-4; calcium channel voltage-dependent subunit beta 4; dihydropyridine-sensitive L-type, calcium cha
Product Background
Antigen Description
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Pathway
Adrenergic signaling in cardiomyocytes; Arrhythmogenic right ventricular cardiomyopathy; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Cardiac muscle contraction
Citations
Publication ()
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COA
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