The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
Pathway
Adrenergic signaling in cardiomyocytes; Arrhythmogenic right ventricular cardiomyopathy; Arrhythmogenic right ventricular cardiomyopathy (ARVC); Cardiac muscle contraction
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
Have you cited DPABH-03537 in a publication? Let us know and earn a reward for your research.
BERROW, NS; CAMPBELL, V; et al. ANTISENSE DEPLETION OF BETA-SUBUNITS MODULATES THE BIOPHYSICAL AND PHARMACOLOGICAL PROPERTIES OF NEURONAL CALCIUM CHANNELS. JOURNAL OF PHYSIOLOGY-LONDON 482:481-491(1995).
Safayhi, H; Haase, H; et al. L-type calcium channels in insulin-secreting cells: Biochemical characterization and phosphorylation in RINm5F cells. MOLECULAR ENDOCRINOLOGY 11:619-629(1997).
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COA
Certificate of Analysis
