CACNA1S (NP_000060, 1743 a.a. ~ 1838 a.a) partial recombinant protein with GST tag. The sequence is CPRVESSMPEDRKSSTPGSLHEETPHSRSTRENTSRCSAPATALLIQKALVRGGLGTLAA DANFIMATGQALGDACQMEPEEVEIMATELLKGREA
This gene encodes one of the five subunits of the slowly inactivating L-type voltage-dependent calcium channel in skeletal muscle cells. Mutations in this gene have been associated with hypokalemic periodic paralysis, thyrotoxic periodic paralysis and malignant hyperthermia susceptibility.
Pathway
Adrenergic signaling in cardiomyocytes; Alzheimers disease; Alzheimers Disease; Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Citations
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