Anti-C1S monoclonal antibody, clone FQS0177(C)

Antibody Isotype

IgG

Clone

FQS0177(C)

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to residues in Human C1s.

Conjugate

Application Notes

Flow Cyt: 1/10 - 1/100; IHC-P: 1/100 - 1/250; WB: 1/1000 - 1/10000.

Alternative Names

C1S; complement component 1, s subcomponent; complement C1s subcomponent; C1 esterase; basic proline-rich peptide IB-1; complement component 1 subcomponent s; FLJ44757;

Entrez Gene ID

UniProt ID

Antigen Description

C1s B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.

Pathway

Classical antibody-mediated complement activation, organism-specific biosystem; Complement Activation, Classical Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem;