Anti-C1S monoclonal antibody, clone 5E0

Antibody Isotype

IgG1

Clone

5E0

Species Reactivity

Mouse; Rat; Dog; Human; Monkey

Immunogen

Recombinant full length Human C1s produced in HEK293T cells (NP_001725).

Conjugate

Application Notes

WB: 1/200 - 1/500;

Alternative Names

C1S; complement component 1, s subcomponent; complement C1s subcomponent; C1 esterase; basic proline-rich peptide IB-1; complement component 1 subcomponent s; FLJ44757;

Entrez Gene ID

UniProt ID

Antigen Description

C1s B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.

Pathway

Classical antibody-mediated complement activation, organism-specific biosystem; Complement Activation, Classical Pathway, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Creation of C4 and C2 activators, organism-specific biosystem;