Anti-S-100 monoclonal antibody (DMAB5483MB)

Mouse anti-Bovine S-100 monoclonal antibody for IHC Datasheet

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Host Species
Antibody Isotype
Species Reactivity
BALB/C mice were immunized with purified bovine brain S-100 protein.


Alternative Names
S100B; S100 calcium binding protein B; protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100-B
Entrez Gene ID
UniProt ID

Product Background

Antigen Description
S-100 protein is a family of low molecular weight protein found in vertebrates characterized by two calcium binding sites of the helix-loop-helix ("EF-hand type") conformation. There are at least 21 different types of S100 proteins. The name is derived from the fact that the protein is 100% Soluble in ammonium sulfate at neutral pH. The function about S-100 antigen include RAGE receptor binding; S100 beta binding; calcium ion binding; calcium-dependent protein binding; kinase inhibitor activity; protein binding; protein homodimerization activity; tau protein binding; zinc ion binding.
Activated TLR4 signalling; Immune System; Innate Immune System; MyD88 cascade initiated on plasma membrane; MyD88 dependent cascade initiated on endosome; MyD88-independent cascade initiated on plasma membrane; MyD88:Mal cascade initiated on plasma membra.


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Kluft, C; van Leuven, CJM; et al. Consequences for the APTT due to direct action of factor XIa on factor X, resulting in bypassing factors VIII-IX. THROMBOSIS RESEARCH 135:198-204(2015).
Alves, MGO; Chagas, LR; et al. Metastatic melanoma of the tongue: a case report with immunohistochemical profile. GERODONTOLOGY 31:314-319(2014).

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