Anti-ATP6V1B1 monoclonal antibody (DCABH-618)

Mouse anti-Human ATP6V1B1 monoclonal antibody for WB, IHC-P Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
4C22
Species Reactivity
Human
Immunogen
Recombinant full length Human ATP6V1B1 produced in HEK293T cells (NP_001683).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; IHC-P: 1/150;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ATP6V1B1; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1; ATP6B1, vacuolar proton pump 3 , VPP3; V-type proton ATPase subunit B, kidney isoform; Renal tubular acidosis with deafness; RTA1B
Entrez Gene ID
UniProt ID

Product Background


Pathway
Collecting duct acid secretion, organism-specific biosystem; Collecting duct acid secretion, conserved biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; Insulin receptor recycling, organism-specific biosystem; Iron uptake and transport, organism-specific biosystem; Metabolic pathways, organism-specific biosystem;

Citations


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References


Li, XM; Sanneman, JD; et al. SLC26A4 Targeted to the Endolymphatic Sac Rescues Hearing and Balance in Slc26a4 Mutant Mice. PLOS GENETICS 9:-(2013).
Yashima, T; Noguchi, Y; et al. Novel ATP6V1B1 mutations in distal renal tubular acidosis and hearing loss. ACTA OTO-LARYNGOLOGICA 130:1002-1008(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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