Anti-ATP6V0A2 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human ATP6V0A2 is used for rabbit immunization.

Conjugate

Alternative Names

ATP6V0A2; ATPase, H+ transporting, lysosomal V0 subunit a2; A2; RTF; TJ6; WSS; ARCL; J6B7; STV1; TJ6M; TJ6S; VPH1; ARCL2A; ATP6A2; ATP6N1D; V-type proton ATPase 116 kDa subunit a isoform 2; A2V-ATPase; v-ATPase 116 kDa; regeneration and tolerance factor;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components. V-ATPase is comprised of a membrane peripheral V(1) domain for ATP hydrolysis, and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is a component of the V(0) domain. Mutations in this gene are a cause of both cutis laxa type II and wrinkly skin syndrome.

Pathway

Collecting duct acid secretion; Collecting duct acid secretion; Disease; Epithelial cell signaling in Helicobacter pylori infection; Epithelial cell signaling in Helicobacter pylori infection; Insulin receptor recycling; Iron uptake and transport; Latent infection of Homo sapiens with Mycobacterium tuberculosis; Lysosome; Lysosome; Oxidative phosphorylation;