Anti-ATP6V0A2 (aa 198-304) polyclonal antibody

Species Reactivity

Human

Immunogen

ATP6V0A2 (NP_036595, 198 a.a. ~ 304 a.a) partial recombinant protein with GST tag. The sequence is GYTIVSYAELDESLEDPETGEVIKWYVFLISFWGEQIGHKVKKICDCYHCHVYPYPNTAE ERREIQEGLNTRIQDLYTVLHKTEDYLRQVLCKAAESVYSRVIQVKK

Conjugate

Alternative Names

ATP6V0A2; ATPase, H+ transporting, lysosomal V0 subunit a2; A2; RTF; TJ6; WSS; ARCL; J6B7; STV1; TJ6M; TJ6S; VPH1; ARCL2A; ATP6A2; ATP6N1D; V-type proton ATPase 116 kDa subunit a isoform 2; A2V-ATPase; v-ATPase 116 kDa; regeneration and tolerance factor;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components. V-ATPase is comprised of a membrane peripheral V(1) domain for ATP hydrolysis, and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is a component of the V(0) domain. Mutations in this gene are a cause of both cutis laxa type II and wrinkly skin syndrome.

Pathway

Collecting duct acid secretion; Disease; Epithelial cell signaling in Helicobacter pylori infection; Iron uptake and transport