Anti-ATL1 (aa 1-100) polyclonal antibody

Species Reactivity

Human

Immunogen

SPG3A (NP_056999, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. The sequence is MAKNRRDRNSWGGFSEKTYEWSSEEEEPVKKAGPVQVLIVKDDHSFELDETALNRILLSE AVRDKEVVAVSVAGAFRKGKSFLMDFMLRYMYNQESVDWV

Conjugate

Alternative Names

ATL1; atlastin GTPase 1; FSP1; GBP3; SPG3; HSN1D; SPG3A; AD-FSP; atlastin1; atlastin-1; GBP-3; hGBP3; GTP-binding protein 3; guanylate-binding protein 3; spastic paraplegia 3 protein A; brain-specific GTP-binding protein; guanine nucleotide-binding protei

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.