Anti-ATG5 monoclonal antibody (DCABH-130) Knockout Validated

Rabbit anti-Human ATG5 monoclonal antibody for WB, IP, IHC-P, ICC

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS2866(3)
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide corresponding to residues in Human APG5L/ATG5.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/10000; IP: 1/10 - 1/100; IHC-P: 1/100 - 1/250; ICC: 1/100 - 1/250;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
ATG5; ATG5 autophagy related 5 homolog (S. cerevisiae); APG5 (autophagy 5, S. cerevisiae) like , APG5 autophagy 5 like (S. cerevisiae) , APG5L; autophagy protein 5; APG5; ASP
Entrez Gene ID
UniProt ID

Product Background


Pathway
Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Negative regulators of RIG-I/MDA5 signaling, organism-specific biosystem; RIG-I-like receptor signaling pathway, organism-specific biosystem; RIG-I-like receptor signaling pathway, conserved biosystem; RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways, organism-specific biosystem; Regulation of autophagy, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Li, B; Yue, Y; et al. Blockade of macrophage autophagy ameliorates activated lymphocytes-derived DNA induced murine lupus possibly via inhibition of proinflammatory cytokine production. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 32:705-714(2014).
Eby, KG; Rosenbluth, JM; et al. ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy. MOLECULAR CANCER 9:-(2010).

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