Human ATG5 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

ATG5 peptide corresponds to 14 amino acids near an internal region of ATG5.

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Reconstitution

ATG5 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed.
May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.

Entrez Gene ID

Synonyms

ATG5; autophagy related 5; ASP; APG5; APG5L; hAPG5; APG5-LIKE; autophagy protein 5; apoptosis-specific protein; ATG5 autophagy related 5 homolog;