Anti-ASS1 monoclonal antibody, clone 3D20

Clone

3D20

Species Reactivity

Human; Monkey; Mouse

Immunogen

Recombinant protein corresponding to human ASS1.

Conjugate

Application Notes

WB (1:500-1:2000); Immunohistochemistry (1:200-1:1000); ELISA (1:10000) & The optimal working dilution should be determined by the end user.

Alternative Names

ASS1; argininosuccinate synthase 1; argininosuccinate synthetase , ASS; argininosuccinate synthase; CTLN1; citrulline-aspartate ligase; citrulline--aspartate ligase; argininosuccinate synthetase 1; ASS;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of ASS cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.

Pathway

Alanine and aspartate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;