Anti-ASS1 monoclonal antibody, clone 3C21

Antibody Isotype

IgG1

Clone

3C21

Species Reactivity

Mouse; Rat; Human; Monkey

Immunogen

Purified recombinant fragment of Human ASS1, expressed in E. Coli.

Conjugate

Application Notes

WB: 1/500 - 1/2000; ELISA: 1/10000; Flow Cyt: 1/200 - 1/400; ICC/IF: 1/200 - 1/1000;

Alternative Names

ASS1; argininosuccinate synthase 1; argininosuccinate synthetase , ASS; argininosuccinate synthase; CTLN1; citrulline-aspartate ligase; citrulline--aspartate ligase; argininosuccinate synthetase 1; ASS;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 14 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromosome 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.

Pathway

Alanine and aspartate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;