Anti-ASS1 monoclonal antibody, clone FQS23400(C)

Antibody Isotype

IgG

Clone

FQS23400(C)

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human ASS1 aa 350 to the C-terminus (C terminal) (Cysteine residue). The exact sequence is proprietary.Database link: P00966

Conjugate

Application Notes

IP: 1/10 - 1/100; WB: 1/1000 - 1/10000; ICC/IF: 1/50 - 1/100.

Alternative Names

ASS1; argininosuccinate synthase 1; argininosuccinate synthetase , ASS; argininosuccinate synthase; CTLN1; citrulline-aspartate ligase; citrulline--aspartate ligase; argininosuccinate synthetase 1; ASS;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene catalyzes the penultimate step of the arginine biosynthetic pathway. There are approximately 10 to 15 copies of this gene including the pseudogenes scattered across the human genome, among which the one located on chromoso 9 appears to be the only functional gene for argininosuccinate synthetase. Mutations in the chromosome 9 copy of this gene cause citrullinemia. Two transcript variants encoding the same protein have been found for this gene.

Pathway

Alanine and aspartate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Arginine and proline metabolism, organism-specific biosystem; Arginine and proline metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem;