Rabbit Anti-Human ARHGEF9 Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

A synthesized peptide derived from human ARHGEF9.

Conjugate

Application Notes

IHC 1:50-1:200
IF/ICC 1:100-1:500

General Notes

This product (Catalog No. DPABH-28910) is a rabbit-derived polyclonal antibody raised against human ARHGEF9. This antibody exhibits cross-reactivity with ARHGEF9 from mouse and rat. It has been affinity purified by Protein A. The protein encoded by this gene is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes. This brain-specific protein also acts as an adaptor protein for the recruitment of gephyrin and together these proteins facilitate receceptor recruitement in GABAnergic and glycinergic synapses. Defects in this gene are the cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy, as well as several other types of cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene.
DPABH-28910 is suitable for use in IHC 1 (50-1:200), IF/ICC 1 (100-1:500) applications.
DPABH-28910 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Entrez Gene ID

UniProt ID