Anti-AKT1 monoclonal antibody (DCABH-59)
Mouse Anti-Human AKT1 monoclonal antibody for IP, WB, ELISA, IHC-P
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Synthetic peptide corresponding to residues surrounding the internal sequence amino acid T308 of Human AKT1 protein.
WB: 1/500 - 1/3000; ELISA: 1/20000; IHC-P: 20 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
AKT1; v-akt murine thymoma viral oncogene homolog 1; RAC-alpha serine/threonine-protein kinase; AKT; PKB; PRKBA
AKT phosphorylates targets in the cytosol, organism-specific biosystem; AKT phosphorylates targets in the nucleus, organism-specific biosystem; AKT-mediated inactivation of FOXO1A, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem;
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Sundstrom, JM; Sundstrom, CJ; et al. Phosphorylation Site Mapping of Endogenous Proteins: A Combined MS and Bioinformatics Approach. JOURNAL OF PROTEOME RESEARCH 8:798-807(2009).
Byun, HJ; Hong, IK; et al. A splice variant of CD99 increases motility and MMP-9 expression of human breast cancer cells through the AKT-, ERK-, and JNK-dependent AP-1 activation signaling pathways. JOURNAL OF BIOLOGICAL CHEMISTRY 281:34833-34847(2006).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.